MKNK1 Antikörper

Produktnummer ABIN1944924

Zitiert in 3+ Publikationen. Dieser Anti-MKNK1-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von MKNK1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MKNK1 Antikörper (ABIN1944924)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MKNK1 Antikörper

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:250-1:1000. WB: 1:250-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-MKNK1 Antikörper (ABIN1944924)

OLoghlen, González, Piñeiro, Pérez-Morgado, Salinas, Martín: "Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1." in: Experimental cell research, Vol. 299, Issue 2, pp. 343-55, (2004) (PubMed).

Knauf, Tschopp, Gram: "Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2." in: Molecular and cellular biology, Vol. 21, Issue 16, pp. 5500-11, (2001) (PubMed).

Fukunaga, Hunter: "MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates." in: The EMBO journal, Vol. 16, Issue 8, pp. 1921-33, (1997) (PubMed).

Details zu MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Andere Bezeichnung: Mnk1

Hintergrund: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.

Molekulargewicht: 51342 Da

Gen-ID: 8569

UniProt: Q9BUB5

Pathways: MAPK Signalweg, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor