C1S Antikörper

Produktnummer ABIN1944822

Dieses Anti-C1S-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von C1S in WB und IHC. Geeignet für Human. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für C1S Antikörper (ABIN1944822)

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-C1S Antikörper

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000. IHC: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-C1S Antikörper (ABIN1944822)

Endo, Takahashi, Nakao, Saiga, Sekine, Matsushita, Nonaka, Fujita: "Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 9, pp. 4924-30, (1998) (PubMed).

Mackinnon, Carter, Smyth, Dunbar, Fothergill: "Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence." in: European journal of biochemistry / FEBS, Vol. 169, Issue 3, pp. 547-53, (1988) (PubMed).

Kusumoto, Hirosawa, Salier, Hagen, Kurachi: "Human genes for complement components C1r and C1s in a close tail-to-tail arrangement." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 19, pp. 7307-11, (1988) (PubMed).

Tosi, Duponchel, Meo, Julier: "Complete cDNA sequence of human complement Cls and close physical linkage of the homologous genes Cls and Clr." in: Biochemistry, Vol. 26, Issue 26, pp. 8516-24, (1988) (PubMed).

Details zu C1S

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Andere Bezeichnung: C1S

Hintergrund: C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

Molekulargewicht: 76684 Da

Gen-ID: 716

UniProt: P09871

Pathways: Komplementsystem