Melatonin Receptor 1B Antikörper

Produktnummer ABIN1944815

Der Kaninchen Polyklonal Anti-Melatonin Receptor 1B-Antikörper wurde für WB validiert. Er ist geeignet, Melatonin Receptor 1B in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Melatonin Receptor 1B Antikörper (ABIN1944815)

Target: Melatonin Receptor 1B (MTNR1B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melatonin Receptor 1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Melatonin Receptor 1B Antikörper

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-Melatonin Receptor 1B Antikörper (ABIN1944815)

Ebisawa, Uchiyama, Kajimura, Kamei, Shibui, Kim, Kudo, Iwase, Sugishita, Jodoi, Ikeda, Ozeki, Watanabe, Sekimoto, Katoh, Yamada, Toyoshima, Okawa, Takahashi, Yamauchi: "Genetic polymorphisms of human melatonin 1b receptor gene in circadian rhythm sleep disorders and controls." in: Neuroscience letters, Vol. 280, Issue 1, pp. 29-32, (2000) (PubMed).

Reppert, Godson, Mahle, Weaver, Slaugenhaupt, Gusella: "Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 19, pp. 8734-8, (1995) (PubMed).

Details zu Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Hintergrund: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Molekulargewicht: 40188 Da

Gen-ID: 4544

UniProt: P49286