NCF1 Antikörper

Produktnummer ABIN1944805

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NCF1 in WB und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für NCF1 Antikörper (ABIN1944805)

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NCF1 Antikörper

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IF: 1:100. WB: 1:250-1:1000. WB: 1:250-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C,-20 °C

Referenzen für anti-NCF1 Antikörper (ABIN1944805)

Görlach, Lee, Roesler, Hopkins, Christensen, Green, Chanock, Curnutte: "A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease." in: The Journal of clinical investigation, Vol. 100, Issue 8, pp. 1907-18, (1997) (PubMed).

Rodaway, Teahan, Casimir, Segal, Bentley: "Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid." in: Molecular and cellular biology, Vol. 10, Issue 10, pp. 5388-96, (1990) (PubMed).

Volpp, Nauseef, Donelson, Moser, Clark: "Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 18, pp. 7195-9, (1989) (PubMed).

Lomax, Leto, Nunoi, Gallin, Malech: "Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease." in: Science (New York, N.Y.), Vol. 245, Issue 4916, pp. 409-12, (1989) (PubMed).

Details zu NCF1

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Andere Bezeichnung: p47 phox

Hintergrund: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

Molekulargewicht: 44652 Da

Gen-ID: 653361

UniProt: P14598

Pathways: PI3K-Akt Signalweg