CEACAM5 Antikörper

Produktnummer ABIN192374

Der Maus Monoklonal Anti-CEACAM5-Antikörper wurde für FACS, IHC (p), IHC (fro) und IP validiert. Er ist geeignet, CEACAM5 in Proben von Human zu detektieren.

Kurzübersicht für CEACAM5 Antikörper (ABIN192374)

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Klon: CB30

Produktdetails anti-CEACAM5 Antikörper

Verwendungszweck: Anti-Hu CD66e Purified

Spezifität: The mouse monoclonal antibody CB30 recognizes CD66e (CEA, 180-200 kDa), an extracellular cell surface-bound carcinoembryonic antigen mainly expressed on epithelial cells.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human carcinoembryonic antigen (CEA, CEACAM5)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (paraffin sections): Staining technique: standard ABC technique (DAB+), recommended dilution: 10 μg/mL (1:100), positive tissue: adenocarcinoma of colon, pretreatment: 0,1 % pepsin in 0,1 M HCl for 30 min at room temperature.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Andere Bezeichnung: CD66e

Hintergrund: Carcinoembryonic antigen related cell adhesion mol,The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.,CEACAM5, CEA

Gen-ID: 1048

UniProt: P06731