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HLA-DP/DR Antikörper (FITC)

This anti-HLA-DP/DR antibody (ABIN192205) is a Mouse Monoclonal antibody detecting HLA-DP/DR in FACS. Suitable for Human.
Produktnummer ABIN192205

Kurzübersicht für HLA-DP/DR Antikörper (FITC) (ABIN192205)

Target

HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Reaktivität

  • 15
  • 5
Human

Wirt

  • 15
Maus

Klonalität

  • 15
Monoklonal

Konjugat

  • 4
  • 4
  • 3
  • 2
  • 2
Dieser HLA-DP/DR Antikörper ist konjugiert mit FITC

Applikation

  • 15
  • 8
  • 8
  • 5
  • 3
Flow Cytometry (FACS)

Klon

MEM-136
  • Verwendungszweck

    Anti-HLA-DR/DP FITC

    Spezifität

    The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    PHA-activated peripheral blood lymphocytes.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    No reconstitution is necessary.

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." in: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

  • Target

    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

    Andere Bezeichnung

    HLA-DR/DP

    Hintergrund

    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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