HLA-DP/DR Antikörper

Produktnummer ABIN94344

Zitiert in 1 Publikation. Der Maus Monoklonal anti-HLA-DP/DR Antikörper (Klon MEM-136) (ABIN94344) detektiert spezifisch HLA-DP/DR in FACS, IP, WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HLA-DP/DR Antikörper (ABIN94344)

Target: HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-DP/DR Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: MEM-136

Produktdetails anti-HLA-DP/DR Antikörper

Verwendungszweck: Anti-HLA-DR/DP Purified

Kreuzreaktivität (Details): Human

Produktmerkmale: The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: PHA-activated peripheral blood lymphocytes.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.
Western blotting: Recommended dilution: 1 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-HLA-DP/DR Antikörper (ABIN94344)

Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." in: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

Details zu HLA-DP/DR

Target: HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Andere Bezeichnung: HLA-DR/DP

Hintergrund: HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.

Gen-ID: 35