HLA-DP/DR Antikörper (PE)

Produktnummer ABIN192164

Der Maus Monoklonal Anti-HLA-DP/DR-Antikörper wurde für FACS validiert. Er ist geeignet, HLA-DP/DR in Proben von Human und Schwein zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für HLA-DP/DR Antikörper (PE) (ABIN192164)

Target: HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Reaktivität: Human, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-DP/DR Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: HL-38

Produktdetails anti-HLA-DP/DR Antikörper (PE)

Verwendungszweck: Anti-HLA-DR/DP PE

Spezifität: The antibody HL-38 recognizes an extracellular common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

Kreuzreaktivität (Details): Human, Porcine

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Raji Burkitt's lymphoma cell line

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.
Avoid prolonged exposure to light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Referenzen für anti-HLA-DP/DR Antikörper (PE) (ABIN192164)

Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

Details zu HLA-DP/DR

Target: HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Andere Bezeichnung: HLA-DR/DP

Hintergrund: HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.