PPARG Antikörper
Kurzübersicht für PPARG Antikörper (ABIN191899)
Target
Alle PPARG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The antibody recognizes a ~33 kDa band, corresponding to PPARgamma isoform CRA-c).
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Aufreinigung
- Affinity chromatography
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Immunogen
- Synthetic peptide surrounding amino acid 262 of human PPAR gamma isoform CRA-c
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Applikationshinweise
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Western blotting (0.5-4 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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Andere Bezeichnung
- PPAR-gamma
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Hintergrund
- PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPAR gamma is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism, PPARgamma also modulates insulin sensitivity, cell proliferation and inflammation. The inhibition of PPAR gamma transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARgamma.Synonyms: NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma
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Gen-ID
- 5468
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NCBI Accession
- NP_005028
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UniProt
- P37231
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Pathways
- MAPK Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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