CAMK2A Antikörper (AA 7-20)
Kurzübersicht für CAMK2A Antikörper (AA 7-20) (ABIN1888861)
Target
Alle CAMK2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 7-20
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Verwendungszweck
- Anti-CaMKII Rabbit Polyclonal Antibody
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Kreuzreaktivität
- Huhn, Rind (Kuh), Meerschweinchen, Hamster, Human, Maus, Kaninchen, Ratte
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Aufreinigung
- Affinity - Purified
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Immunogen
- Synthetic peptide corresponding to aa 7-20 (N-terminus) of rat CaMKII delta isoform conjugated to KLH.
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Applikationshinweise
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Immunoblotting: Use at 1-5 μg/mL. A band of ~50-60 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
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Konzentration
- Lot specific
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Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- This antibody is stable for at least one (1) year at -20°C.
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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Andere Bezeichnung
- CAMK2A
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Hintergrund
- Calcium/calmodulin-dependent protein kinase type II subunit α,Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimer's disease, Angelman syndrome, and heart arrhythmia.,CaM kinase II subunit α, CaMK-II subunit α, EC 2.7.11.17
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Gen-ID
- 815
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NCBI Accession
- NP_741960
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Pathways
- WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
Target
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