DCAF12 Antikörper (C-Term)

Produktnummer ABIN1887065

Der Kaninchen Polyklonal Anti-DCAF12-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, DCAF12 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für DCAF12 Antikörper (C-Term) (ABIN1887065)

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCAF12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-DCAF12 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human TCC52.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu DCAF12

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Andere Bezeichnung: TCC52

Hintergrund: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types.Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors.One such CT antigen is TCC52, a novel centrosomal protein.TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.The normal biological function of this protein is not known at this time.
Synonyms: Testis cancer centrosome-related protein 52, DDB1 and CUL4 associated factor 12, DCAF12, CT102, WDR40A

NCBI Accession: NP_056212