Caspase 4 Antikörper (AA 91-105)

Produktnummer ABIN1886902

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Caspase 4 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Caspase 4 Antikörper (AA 91-105) (ABIN1886902)

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Caspase 4 Antikörper

Bindungsspezifität: AA 91-105

Aufreinigung: Ion exchange chromatography purified

Immunogen: Peptide corresponding to amino acids 91 to 105 of human caspase-13.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu Caspase 4

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Andere Bezeichnung: Caspase-13

Hintergrund: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases.A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13.Caspase-13 belongs to the ICE subfamily of caspases.Overexpression of caspase-13 induces apoptosis.Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis.Caspase-13 is expressed in a variety of human tissues and cell lines.
Synonyms: Casp-13, ERICE

Molekulargewicht: 43 kDa

UniProt: O75601

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity