CIDEB Antikörper (AA 204-219)

Produktnummer ABIN1886856

Dieses Anti-CIDEB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CIDEB in ELISA und WB. Geeignet für Maus.

Kurzübersicht für CIDEB Antikörper (AA 204-219) (ABIN1886856)

Target: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEB Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-CIDEB Antikörper

Bindungsspezifität: AA 204-219

Kreuzreaktivität (Details): It has no cross activity to CIDE-A.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 204 to 219 of murine CIDE-B.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CIDEB

Target: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Andere Bezeichnung: CIDE-B

Hintergrund: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase.DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified.CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD.Expression of CIDE-B induces apoptosis, which is inhibited by DFF45.CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation.CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.

Molekulargewicht: 25 kDa