TRAF3IP2 Antikörper (AA 2-15)

Produktnummer ABIN1886846

Produktdetails anti-TRAF3IP2 Antikörper

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Bindungsspezifität: AA 2-15

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 2 to 15 of human CIKS.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Andere Bezeichnung: CIKS (TRAF3IP2 Produkte)

Synonyme: ACT1 antikoerper, C6orf2 antikoerper, C6orf4 antikoerper, C6orf5 antikoerper, C6orf6 antikoerper, CIKS antikoerper, PSORS13 antikoerper, AI429613 antikoerper, Act1 antikoerper, RGD1304768 antikoerper, C6ORF4 antikoerper, t3jam antikoerper, traf3ip2 antikoerper, TRAF3IP2 antikoerper, MGC134034 antikoerper, TRAF3 interacting protein 2 antikoerper, Traf3 interacting protein 2 antikoerper, adapter protein CIKS antikoerper, TRAF3 interacting protein 2 L homeolog antikoerper, TRAF3IP2 antikoerper, Traf3ip2 antikoerper, LOC100473939 antikoerper, traf3ip3.L antikoerper, traf3ip3 antikoerper

Hintergrund: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses.NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli.NF-kappaB associates with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity.IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma.A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappaB activator 1).CIKS directly interacts with IKKgamma.CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK).These results indicate that CIKS/Act1 is involved in the inflammation and stress responses.CIKS/Act1 is ubiquitously expressed in human tissues.
Synonyms: Act1

Molekulargewicht: 63 kDa

Pathways: Production of Molecular Mediator of Immune Response