STS Antikörper (AA 182-195)

Produktnummer ABIN1886844

Dieses Anti-STS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STS in WB, ELISA und ICC. Geeignet für Human.

Kurzübersicht für STS Antikörper (AA 182-195) (ABIN1886844)

Target: STS (Steroid Sulfatase (STS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-STS Antikörper

Bindungsspezifität: AA 182-195

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 182 to 195 of human ASC.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu STS

Target: STS (Steroid Sulfatase (STS))

Andere Bezeichnung: ASC

Hintergrund: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1.Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4).Overexpression of ASC/TMS1 induced DNA fragmentation.ASC/TMS1 is expressed in a variety of human and mouse tissues.

Molekulargewicht: 25 kDa

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation