RHOA Antikörper (AA 101-150)

Produktnummer ABIN1886746

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RHOA in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RHOA Antikörper (AA 101-150) (ABIN1886746)

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RHOA Antikörper

Bindungsspezifität: AA 101-150

Immunogen: KLH conjugated synthetic peptide derived from human RhoA (101-150aa)

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.100-1.500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS, pH 7.4 with 10 mg/ml BSA and 0.1 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C/1 year

Haltbarkeit: 12 months

Details zu RHOA

Target: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Andere Bezeichnung: RhoA

Hintergrund: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane.It is thought to be important in cell locomotion.Overexpression of this gene is associated with tumor cell proliferation and metastasis.Multiple alternatively spliced variants, encoding the same protein, have been identified.References: Graham D.L.et al.Chem.Biol.9:375-381(2002) Snyder J.T.et al.Nat.Struct.Biol.9:468-475(2002) Longenecker K.et al.Acta Crystallogr.D 59:876-880(2003)
Synonyms: RhoA protein, Aplysia ras related homolog 12, ARH 12, ARH12

Molekulargewicht: 21 kDa

UniProt: P61586

Pathways: Microtubule Dynamics, WNT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interaktom