DDB1 Antikörper (AA 749-1123)

Produktnummer ABIN1886645

Der Kaninchen Polyklonal Anti-DDB1-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, DDB1 in Proben von Human zu detektieren.

Kurzübersicht für DDB1 Antikörper (AA 749-1123) (ABIN1886645)

Target: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-DDB1 Antikörper

Bindungsspezifität: AA 749-1123

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 749 and 1123 of DDB1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu DDB1

Target: DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Andere Bezeichnung: DDB1

Hintergrund: This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit.This protein functions in nucleotide-excision repair.Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE).However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit.In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.[provided by RefSeq]

Molekulargewicht: 127 kDa

Gen-ID: 1642

NCBI Accession: NM_001923, NP_001914

Pathways: DNA Reparatur