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TYK2 Antikörper (AA 680-1176)

TYK2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN1886613

Datenblatt (PDF)

Target Alle TYK2 Antikörper anzeigen

TYK2 (Tyrosine Kinase 2 (TYK2))
Bindungsspezifität
20

16

15

8

7

5

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 680-1176
Reaktivität
78

29

22

4

2

2

1

1

1
Human
Wirt
72

6
Kaninchen
Passende Sekundärantikörper
Klonalität
72

7
Polyklonal
Konjugat
36

6

5

5

3

2

2

2

2

2

2

2

2

2

2

2

2
Dieser TYK2 Antikörper ist unkonjugiert
Applikation
62

38

20

13

13

12

10

6

4

2

2
Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung

Purified by antigen-affinity chromatography.

Immunogen

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 1176 of TYK2

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anti-Tyrosine Kinase 2 (TYK2) (AA 1020-1069) antibody
TYK2 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung

TYK2 (TYK2 Produkte)

Synonyme

JTK1 antikoerper, tyrosine kinase 2 antikoerper, TYK2 antikoerper, Tyk2 antikoerper

Hintergrund

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families.This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits.It is also component of both the type I and type III interferon signaling pathways.As such, it may play a role in anti-viral immunity.A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.[provided by RefSeq]

Molekulargewicht

134 kDa

Gen-ID

7297

NCBI Accession

NM_003331, NP_003322

Pathways

JAK-STAT Signalweg, Hepatitis C