RASSF1 Antikörper (AA 50-334)

Produktnummer ABIN1886518

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RASSF1 in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RASSF1 Antikörper (AA 50-334) (ABIN1886518)

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RASSF1 Antikörper

Bindungsspezifität: AA 50-334

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 50 and 334 of RASSF1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu RASSF1

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Andere Bezeichnung: RASSF1

Hintergrund: This gene encodes a protein similar to the RAS effector proteins.Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene.The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region.The encoded protein was found to interact with DNA repair protein XPA.The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]

Molekulargewicht: 39 kDa

Gen-ID: 11186

NCBI Accession: NP_733832, NM_170714