Desmocollin 2 Antikörper (AA 480-676)

Produktnummer ABIN1886508

Dieses Anti-Desmocollin 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Desmocollin 2 in WB und IHC. Geeignet für Human.

Kurzübersicht für Desmocollin 2 Antikörper (AA 480-676) (ABIN1886508)

Target: Desmocollin 2 (DSC2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Desmocollin 2 Antikörper

Bindungsspezifität: AA 480-676

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 480 and 676 of Desmocollin 2

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Desmocollin 2

Target: Desmocollin 2 (DSC2)

Andere Bezeichnung: Desmocollin 2

Hintergrund: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily.These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation.The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.Alternative splicing results in two transcript variants encoding distinct isoforms.[provided by RefSeq]

Molekulargewicht: 94 kDa

Gen-ID: 1824

NCBI Accession: NM_004949, NP_004940