Prohibitin 2 Antikörper (AA 45-298)
Kurzübersicht für Prohibitin 2 Antikörper (AA 45-298) (ABIN1886480)
Target
Alle Prohibitin 2 (PHB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 45-298
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 45 and 298 of REA
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Applikationshinweise
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Prohibitin 2 (PHB2)
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Andere Bezeichnung
- REA
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Hintergrund
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Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity).Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens.Competes with NCOA1 for modulation of ER transcriptional activity.Probably involved in regulating mitochondrial respiration activity and in aging.
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Molekulargewicht
- 33 kDa
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Gen-ID
- 11331
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NCBI Accession
- NM_007273, NP_009204
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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