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GLE1 Antikörper (AA 414-656)

Dieses Anti-GLE1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLE1 in WB, IHC und IF. Geeignet für Human.
Produktnummer ABIN1886454

Kurzübersicht für GLE1 Antikörper (AA 414-656) (ABIN1886454)

Target

Alle GLE1 Antikörper anzeigen
GLE1 (GLE1 RNA Export Mediator (GLE1))

Reaktivität

  • 16
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 14
  • 3
Kaninchen

Klonalität

  • 16
  • 1
Polyklonal

Konjugat

  • 13
  • 2
  • 1
  • 1
Dieser GLE1 Antikörper ist unkonjugiert

Applikation

  • 12
  • 9
  • 6
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 414-656

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 656 of GLE1
  • Applikationshinweise

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    Biohazard Informations: This product contains thimerosal which is hazardous.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target

    GLE1 (GLE1 RNA Export Mediator (GLE1))

    Andere Bezeichnung

    GLE1

    Hintergrund

    This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export.Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export.Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes.This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

    Molekulargewicht

    75 kDa

    Gen-ID

    2733

    NCBI Accession

    NM_001499, NP_001490
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