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GLE1 Antikörper (AA 414-656)

GLE1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1886454
  • Target Alle GLE1 Antikörper anzeigen
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 414-656
    Reaktivität
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 11
    • 3
    Kaninchen
    Klonalität
    • 13
    • 1
    Polyklonal
    Konjugat
    • 10
    • 2
    • 1
    • 1
    Dieser GLE1 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 656 of GLE1
    Top Product
    Discover our top product GLE1 Primärantikörper
  • Applikationshinweise
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    Biohazard Informations: This product contains thimerosal which is hazardous.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Andere Bezeichnung
    GLE1 (GLE1 Produkte)
    Hintergrund
    This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export.Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export.Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes.This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
    Molekulargewicht
    75 kDa
    Gen-ID
    2733
    NCBI Accession
    NM_001499, NP_001490
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