B-Cell Linker Antikörper (AA 394-456)

Produktnummer ABIN1886429

Der Kaninchen Polyklonal Anti-B-Cell Linker-Antikörper wurde für WB und IF validiert. Er ist geeignet, B-Cell Linker in Proben von Human zu detektieren.

Kurzübersicht für B-Cell Linker Antikörper (AA 394-456) (ABIN1886429)

Target: B-Cell Linker (BLNK)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser B-Cell Linker Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-B-Cell Linker Antikörper

Bindungsspezifität: AA 394-456

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 394 and 456 of BLNK

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu B-Cell Linker

Target: B-Cell Linker (BLNK)

Andere Bezeichnung: B-cell linker protein

Hintergrund: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions.The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation.Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked.Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molekulargewicht: 50 kDa

Gen-ID: 29760

NCBI Accession: NP_037446, NM_013314

Pathways: BCR Signaling