IL12RB2 Antikörper (AA 323-665)

Produktnummer ABIN1886370

Der Kaninchen Polyklonal anti-IL12RB2 Antikörper (ABIN1886370) detektiert spezifisch IL12RB2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL12RB2 Antikörper (AA 323-665) (ABIN1886370)

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL12RB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL12RB2 Antikörper

Bindungsspezifität: AA 323-665

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 323 and 665 of Human IL12RB2

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu IL12RB2

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Hintergrund: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex.The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.[provided by RefSeq]

Molekulargewicht: 97 kDa

Gen-ID: 3595

NCBI Accession: NM_001559, NP_001550

Pathways: JAK-STAT Signalweg