GAD Antikörper (AA 280-582)

Produktnummer ABIN1886309

Der Kaninchen Polyklonal Anti-GAD-Antikörper wurde für WB und IF validiert. Er ist geeignet, GAD in Proben von Human zu detektieren.

Kurzübersicht für GAD Antikörper (AA 280-582) (ABIN1886309)

Target: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-GAD Antikörper

Bindungsspezifität: AA 280-582

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 280 and 582 of GAD1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu GAD

Target: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Andere Bezeichnung: GAD67

Hintergrund: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes.The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid.A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes.This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.[provided by RefSeq]

Molekulargewicht: 67 kDa

Gen-ID: 2571

NCBI Accession: NP_000808, NM_000817