Complement C2 Antikörper (AA 265-612)

Produktnummer ABIN1886288

Der Kaninchen Polyklonal Anti-Complement C2-Antikörper wurde für WB und IF validiert. Er ist geeignet, Complement C2 in Proben von Human zu detektieren.

Kurzübersicht für Complement C2 Antikörper (AA 265-612) (ABIN1886288)

Target: Complement C2

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Complement C2 Antikörper

Bindungsspezifität: AA 265-612

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 265 and 612 of Human C2

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Complement C2

Target: Complement C2

Hintergrund: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system.Activated C1 cleaves C2 into C2a and C2b.The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase.Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration.This gene localizes within the class III region of the MHC on the short arm of chromosome 6.Alternative splicing results in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Molekulargewicht: 83 kDa

Gen-ID: 717

NCBI Accession: NP_000054, NM_000063