MMP2 Antikörper (AA 193-545)

Produktnummer ABIN1886151

Dieses Anti-MMP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MMP2 in WB und IF. Geeignet für Human.

Kurzübersicht für MMP2 Antikörper (AA 193-545) (ABIN1886151)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-MMP2 Antikörper

Bindungsspezifität: AA 193-545

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 193 and 545 of Human MMP2

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes.The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molekulargewicht: 74 kDa

Gen-ID: 4313

NCBI Accession: NM_004530, NP_004521

Pathways: Activation of Innate immune Response