BCCIP Antikörper (AA 181-233)

Produktnummer ABIN1886127

Der Kaninchen Polyklonal anti-BCCIP Antikörper (ABIN1886127) detektiert spezifisch BCCIP in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BCCIP Antikörper (AA 181-233) (ABIN1886127)

Target: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCCIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-BCCIP Antikörper

Bindungsspezifität: AA 181-233

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 181 and 233 (Q9P287) of BCCIP

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu BCCIP

Target: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Hintergrund: This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins.It is an evolutionarily conserved nuclear protein with multiple interacting domains.The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium.Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21.This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression.Multiple transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq]

Molekulargewicht: 36 kDa

Gen-ID: 56647

NCBI Accession: NM_016567, NP_057651