BCCIP Antikörper
Kurzübersicht für BCCIP Antikörper (ABIN7264637)
Target
Alle BCCIP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human BCCIP (NP_510868.1).
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Isotyp
- IgG
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anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibody
BCCIP Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-322) antibodyBCCIP Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 300-350) antibodyBCCIP Reaktivität: Human IHC, IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 1-314) antibodyBCCIP Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (AA 210-314) antibodyBCCIP Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-BRCA2 and CDKN1A Interacting Protein (BCCIP) (C-Term) antibodyBCCIP Reaktivität: Human IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:100-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
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Andere Bezeichnung
- BCCIP
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Hintergrund
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
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Gen-ID
- 56647
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UniProt
- Q9P287
Target
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