IL-24 Antikörper (AA 142-156)

Produktnummer ABIN1886040

Der Kaninchen Polyklonal anti-IL-24 Antikörper (ABIN1886040) detektiert spezifisch IL-24 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-24 Antikörper (AA 142-156) (ABIN1886040)

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-24 Antikörper

Bindungsspezifität: AA 142-156

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 142 and 156 (Q13007) of IL24

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Andere Bezeichnung: Interleukin-24

Hintergrund: This gene encodes a member of the IL10 family of cytokines.It was identified as a gene induced during terminal differentiation in melanoma cells.The protein encoded by this gene can induce apoptosis selectively in various cancer cells.Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis.The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes.Alternatively spliced transcript variants encoding distinct isoforms have been reported.[provided by RefSeq]
Synonyms: C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7

Molekulargewicht: 24 kDa

Gen-ID: 11009

NCBI Accession: NP_006841, NM_006850

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagie