HSPB8 Antikörper (AA 134-196)

Produktnummer ABIN1886015

Der Kaninchen Polyklonal anti-HSPB8 Antikörper wird verwendet zum Nachweis von HSPB8 in Proben von Human. Er wurde validiert für WB, IHC und IF.

Kurzübersicht für HSPB8 Antikörper (AA 134-196) (ABIN1886015)

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-HSPB8 Antikörper

Bindungsspezifität: AA 134-196

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 134 and 196 of HSPB8

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: HSPB8

Hintergrund: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule.The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy.Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.[provided by RefSeq]

Molekulargewicht: 22 kDa

Gen-ID: 26353

NCBI Accession: NM_014365, NP_055180