UNC13D Antikörper (AA 1029-1090)

Produktnummer ABIN1885943

Der Kaninchen Polyklonal anti-UNC13D Antikörper wird verwendet zum Nachweis von UNC13D in Proben von Human. Er wurde validiert für WB, IHC und IF.

Kurzübersicht für UNC13D Antikörper (AA 1029-1090) (ABIN1885943)

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-UNC13D Antikörper

Bindungsspezifität: AA 1029-1090

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1029 and 1090 of Human UNC13D

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu UNC13D

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Andere Bezeichnung: UNC13D

Hintergrund: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins.The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.[provided by RefSeq]

Molekulargewicht: 123 kDa

Gen-ID: 201294

NCBI Accession: NP_954712, NM_199242

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process