MRPL41 Antikörper (AA 1-302)

Produktnummer ABIN1885895

Der Kaninchen Polyklonal anti-MRPL41 Antikörper wird verwendet zum Nachweis von MRPL41 in Proben von Human. Er wurde validiert für WB, IHC und IF.

Kurzübersicht für MRPL41 Antikörper (AA 1-302) (ABIN1885895)

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MRPL41 Antikörper

Bindungsspezifität: AA 1-302

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 302 of PIG3

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Andere Bezeichnung: PIG3

Hintergrund: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation.This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death.It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence.P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence.The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53.It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.At least two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]

Molekulargewicht: 36 kDa

Gen-ID: 9540

NCBI Accession: NM_004881, NP_004872

Pathways: p53 Signalweg