Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
PON2
(Paraoxonase 2 (PON2))
Andere Bezeichnung
PON2
Hintergrund
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7.The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress.Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria.Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq]