DNASE1 Antikörper (AA 1-252)

Produktnummer ABIN1885847

Der Kaninchen Polyklonal anti-DNASE1 Antikörper wird verwendet zum Nachweis von DNASE1 in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für DNASE1 Antikörper (AA 1-252) (ABIN1885847)

Target: DNASE1 (Deoxyribonuclease I (DNASE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-DNASE1 Antikörper

Bindungsspezifität: AA 1-252

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 252 of DNase I

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu DNASE1

Target: DNASE1 (Deoxyribonuclease I (DNASE1))

Andere Bezeichnung: DNase I

Hintergrund: This gene encodes a member of the DNase family.This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner.At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record.Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease.A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.[provided by RefSeq]

Molekulargewicht: 31 kDa

Gen-ID: 1773

NCBI Accession: NM_005223, NP_005214