Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
AIMP1
(Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
Andere Bezeichnung
EMAP II
Hintergrund
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing.The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor.The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells.This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.Multiple transcript variants encoding different isoforms have been found for this gene.A pseudogene has been identified on chromosome 20.[provided by RefSeq] Synonyms: p43, AIMP1, EMAP2, EMAPII