SMC1A Antikörper (AA 1-218)

Produktnummer ABIN1885793

Produktdetails anti-SMC1A Antikörper

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Bindungsspezifität: AA 1-218

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 218 of SMC1A

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu SMC1A

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Andere Bezeichnung: SMC1A (SMC1A Produkte)

Synonyme: CDLS2 antikoerper, DXS423E antikoerper, SB1.8 antikoerper, SMC1 antikoerper, SMC1L1 antikoerper, SMC1alpha antikoerper, SMCB antikoerper, SMC-1A antikoerper, NV15570 antikoerper, 5830426I24Rik antikoerper, Sb1.8 antikoerper, Smc1 antikoerper, Smc1alpha antikoerper, Smc1l1 antikoerper, Smcb antikoerper, mKIAA0178 antikoerper, smc1 antikoerper, smc1a antikoerper, smc1l1 antikoerper, xSMC1 antikoerper, smc1aa antikoerper, structural maintenance of chromosomes 1A antikoerper, structural maintenance of chromosomes 1A b antikoerper, structural maintenance of chromosomes 1A L homeolog antikoerper, SMC1A antikoerper, smc1a antikoerper, Smc1a antikoerper, smc1ab antikoerper, smc1a.L antikoerper

Hintergrund: Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain.Therefore, the encoded protein is thought to be an important part of functional kinetochores.In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair.This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.[provided by RefSeq]

Molekulargewicht: 143 kDa

Gen-ID: 8243

NCBI Accession: NP_006297, NM_006306

Pathways: Stem Cell Maintenance