NK2 Homeobox 5 Antikörper (AA 1-188)

Produktnummer ABIN1885739

Der Kaninchen Polyklonal anti-NK2 Homeobox 5 Antikörper wird verwendet zum Nachweis von NK2 Homeobox 5 in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für NK2 Homeobox 5 Antikörper (AA 1-188) (ABIN1885739)

Target: NK2 Homeobox 5 (NKX2-5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NK2 Homeobox 5 Antikörper

Bindungsspezifität: AA 1-188

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of NKX2-5

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Andere Bezeichnung: NKX2-5

Hintergrund: Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]).It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart.Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation.Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation.CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]
Synonyms: CSX, CSX1, NKX2.5, NKX2E, NKX4-1

Molekulargewicht: 35 kDa

Gen-ID: 1482

NCBI Accession: NM_004387, NP_004378

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development