Endothelin 3 Antikörper (AA 1-187)

Produktnummer ABIN1885737

Dieses Anti-Endothelin 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Endothelin 3 in WB. Geeignet für Human.

Kurzübersicht für Endothelin 3 Antikörper (AA 1-187) (ABIN1885737)

Target: Endothelin 3 (EDN3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Endothelin 3 Antikörper

Bindungsspezifität: AA 1-187

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 187 of Human EDN3

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Endothelin 3

Target: Endothelin 3 (EDN3)

Andere Bezeichnung: ET-3

Hintergrund: The protein encoded by this gene is a member of the endothelin family.Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.The active form of this protein is a 21 amino acid peptide processed from the precursor protein.The active peptide is a ligand for endothelin receptor type B (EDNRB).The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons.Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells.Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.[provided by RefSeq]

Molekulargewicht: 25 kDa

Gen-ID: 1908

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones