GSTa2 Antikörper (AA 1-166)

Produktnummer ABIN1885674

Dieses Anti-GSTa2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GSTa2 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für GSTa2 Antikörper (AA 1-166) (ABIN1885674)

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTa2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GSTa2 Antikörper

Bindungsspezifität: AA 1-166

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 166 of Human GSTA2

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu GSTa2

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Andere Bezeichnung: glutathione S-transferase alpha 2

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class.The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver.In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.[provided by RefSeq]
Synonyms: GST2, GTA2, GTH2, GSTA2-2, MGC10525

Molekulargewicht: 26 kDa

Gen-ID: 2939

NCBI Accession: NP_000837, NM_000846