DUSP8 Antikörper (AA 1-14)

Produktnummer ABIN1885611

Der Kaninchen Polyklonal anti-DUSP8 Antikörper (ABIN1885611) detektiert spezifisch DUSP8 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DUSP8 Antikörper (AA 1-14) (ABIN1885611)

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-DUSP8 Antikörper

Bindungsspezifität: AA 1-14

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human DUSP8

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu DUSP8

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Andere Bezeichnung: DUSP8

Hintergrund: The protein encoded by this gene is a member of the dualprotein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation.Different members of the family of dualphosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.[provided by RefSeq]

Molekulargewicht: 66 kDa

Gen-ID: 1850

NCBI Accession: NP_004411, NM_004420