LITAF Antikörper (AA 1-132)

Produktnummer ABIN1885606

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LITAF in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LITAF Antikörper (AA 1-132) (ABIN1885606)

Target: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LITAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LITAF Antikörper

Bindungsspezifität: AA 1-132

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 132 of Human LITAF

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu LITAF

Target: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Andere Bezeichnung: LITAF

Hintergrund: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators.This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway.Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD).Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq]

Molekulargewicht: 17 kDa

Gen-ID: 9516

NCBI Accession: NM_004862, NP_004853

Pathways: Cellular Response to Molecule of Bacterial Origin