ERCC1 Antikörper (C-Term)

Produktnummer ABIN1882194

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-ERCC1 Antikörper (Klon 752CT13-2-5) (ABIN1882194) detektiert spezifisch ERCC1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ERCC1 Antikörper (C-Term) (ABIN1882194)

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 752CT13-2-5

Produktdetails anti-ERCC1 Antikörper

Bindungsspezifität: AA 268-297, C-Term

Aufreinigung: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This ERCC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the C-terminal region of human ERCC1.

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ERCC1 Antikörper (ABIN1882194)

Yu, Mu, Lee, Okamoto, Reed, Bostick-Bruton, Mitchell, Reed: "A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues." in: Mutation research, Vol. 382, Issue 1-2, pp. 13-20, (1997) (PubMed).

Hoeijmakers, van Duin, Westerveld, Yasui, Bootsma: "Identification of DNA repair genes in the human genome." in: Cold Spring Harbor symposia on quantitative biology, Vol. 51 Pt 1, pp. 91-101, (1987) (PubMed).

van Duin, de Wit, Odijk, Westerveld, Yasui, Koken, Hoeijmakers, Bootsma: "Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10." in: Cell, Vol. 44, Issue 6, pp. 913-23, (1986) (PubMed).

Details zu ERCC1

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Andere Bezeichnung: ERCC1

Hintergrund: Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.

Molekulargewicht: 32562

NCBI Accession: NP_001159521, NP_001974, NP_973730

UniProt: P07992

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response