TUBG1 Antikörper (N-Term)

Produktnummer ABIN1881959

Produktdetails anti-TUBG1 Antikörper

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Bindungsspezifität: AA 23-51, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M, Rat, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TUBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human TUBG1.

Klon: RB40908

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TUBG1 Antikörper (ABIN1881959)

Couch, Wang, Bamlet, de Andrade, Petersen, McWilliams: "Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 251-7, (2010) (PubMed).

Alvarado-Kristensson, Rodríguez, Silió, Valpuesta, Carrera: "SADB phosphorylation of gamma-tubulin regulates centrosome duplication." in: Nature cell biology, Vol. 11, Issue 9, pp. 1081-92, (2009) (PubMed).

Zhang, Chen, Feng, Hou, Yang, Liu, Jiang, Zhang: "Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome." in: Journal of cell science, Vol. 122, Issue Pt 13, pp. 2240-51, (2009) (PubMed).

Details zu TUBG1

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Andere Bezeichnung: TUBG1 (TUBG1 Produkte)

Hintergrund: This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.

Molekulargewicht: 51170

NCBI Accession: NP_001061

UniProt: P23258

Pathways: Microtubule Dynamics, M Phase