TSC1 Antikörper (pThr416)
(2 Referenzen)Kurzübersicht für TSC1 Antikörper (pThr416) (ABIN1881922)
Target
Alle TSC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pThr416
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T416 of mouse TSC1.
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Isotyp
- Ig Fraction
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anti-Tuberous Sclerosis 1 (TSC1) (AA 550-650) antibody
TSC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 3A2 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibodyTSC1 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 5A8 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) antibodyTSC1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB11648 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 101-344) antibodyTSC1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer505) antibodyTSC1 Reaktivität: Human, Maus, Schaf ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer591) antibodyTSC1 Reaktivität: Maus DB Wirt: Kaninchen Polyclonal RB41240 unconjugated
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Applikationshinweise
- DB: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." in: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).
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: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Andere Bezeichnung
- TSC1
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Hintergrund
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
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Molekulargewicht
- 128746
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NCBI Accession
- NP_075025
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UniProt
- Q9EP53
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Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
Target
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