TES Antikörper (N-Term)

Produktnummer ABIN1881876

Dieses Anti-TES-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TES in WB. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für TES Antikörper (N-Term) (ABIN1881876)

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TES Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41857

Produktdetails anti-TES Antikörper

Bindungsspezifität: AA 41-70, N-Term

Homologie: B, C, Hs, Pig, Sh

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TES.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TES Antikörper (ABIN1881876)

Qiu, Zhu, Yuan, Yan, Yang, Kong: "Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer." in: Cancer science, Vol. 101, Issue 5, pp. 1255-60, (2010) (PubMed).

Gunduz, Gunduz, Beder, Nagatsuka, Fukushima, Sutcu, Delibas, Yamanaka, Shimizu, Nagai: "Downregulation of TESTIN and its association with cancer history and a tendency toward poor survival in head and neck squamous cell carcinoma." in: Archives of otolaryngology--head & neck surgery, Vol. 135, Issue 3, pp. 254-60, (2009) (PubMed).

Boëda, Briggs, Higgins, Garvalov, Fadden, McDonald, Way: "Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding." in: Molecular cell, Vol. 28, Issue 6, pp. 1071-82, (2007) (PubMed).

Details zu TES

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Andere Bezeichnung: TES

Hintergrund: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of this gene.

Molekulargewicht: 47996

NCBI Accession: NP_056456, NP_690042

UniProt: Q9UGI8