SEC31A Antikörper (AA 473-502)

Produktnummer ABIN1881783

Produktdetails anti-SEC31A Antikörper

Target: SEC31A (SEC31 Homolog A (SEC31A))

Bindungsspezifität: AA 473-502

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC31A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEC31A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the Central region of human SEC31A.

Klon: RB41562

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SEC31A Antikörper (ABIN1881783)

Fernández, Laguna, Monge, Montiel, Olmos, Pérez, Sánchez-Forcada: "Dendritic (phosphine)gold(I) thiolate complexes: assessment of the molecular size through PGSE NMR studies." in: Dalton transactions (Cambridge, England : 2003), Issue 3, pp. 474-80, (2009) (PubMed).

Shibata, Suzuki, Kakiuchi, Inuzuka, Yoshida, Mizuno, Maki: "Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9623-32, (2008) (PubMed).

Townley, Feng, Schmidt, Carter, Porter, Verkade, Stephens: "Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development." in: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3025-34, (2008) (PubMed).

Details zu SEC31A

Target: SEC31A (SEC31 Homolog A (SEC31A))

Andere Bezeichnung: SEC31A (SEC31A Produkte)

Hintergrund: The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

Molekulargewicht: 133015

NCBI Accession: NP_001070674, NP_001070675, NP_001070676, NP_001177978, NP_055748, NP_057295

UniProt: O94979

Pathways: ER-Nucleus Signaling