SEC31A Antikörper (AA 429-571)

Produktnummer ABIN5542690

Produktdetails anti-SEC31A Antikörper

Target: SEC31A (SEC31 Homolog A (SEC31A))

Bindungsspezifität: AA 429-571

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SEC31A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human SEC31A (AA: 429-571) expressed in E. coli.

Klon: 5D12C6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: , FCM:

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu SEC31A

Target: SEC31A (SEC31 Homolog A (SEC31A))

Andere Bezeichnung: SEC31A (SEC31A Produkte)

Synonyme: ABP125 antikoerper, ABP130 antikoerper, HSPC334 antikoerper, SEC31L1 antikoerper, Sec31l1 antikoerper, VAP1 antikoerper, 1810024J13Rik antikoerper, AU042160 antikoerper, HSPC275 antikoerper, cb354 antikoerper, sec31p antikoerper, zgc:63547 antikoerper, SEC31 homolog A, COPII coat complex component antikoerper, Sec31 homolog A (S. cerevisiae) antikoerper, SEC31A antikoerper, Sec31a antikoerper, sec31a antikoerper

Hintergrund:

Description: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.,

Aliases: ABP125, ABP130, HSPC275, HSPC334, SEC31L1

Molekulargewicht: 133 kDa

Gen-ID: 22872

HGNC: 22872

Pathways: ER-Nucleus Signaling