RPS6 Antikörper (N-Term)

Produktnummer ABIN1881764

Der Kaninchen Polyklonal Anti-RPS6-Antikörper wurde für WB validiert. Er ist geeignet, RPS6 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für RPS6 Antikörper (N-Term) (ABIN1881764)

Target: RPS6 (Ribosomal Protein S6 (RPS6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB41661

Produktdetails anti-RPS6 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Homologie: B, Pr, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RPS6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-RPS6 Antikörper (ABIN1881764)

Glover, Oates, Tang, Moore, Tarnopolsky, Phillips: "Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 295, Issue 2, pp. R604-10, (2008) (PubMed).

Maggi, Kuchenruether, Dadey, Schwope, Grisendi, Townsend, Pandolfi, Weber: "Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7050-65, (2008) (PubMed).

Fujita, Ito, Nakano, Kinoshita, Wate, Kusaka: "Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease." in: Acta neuropathologica, Vol. 116, Issue 4, pp. 439-45, (2008) (PubMed).

Robledo, Idol, Crimmins, Ladenson, Mason, Bessler: "The role of human ribosomal proteins in the maturation of rRNA and ribosome production." in: RNA (New York, N.Y.), Vol. 14, Issue 9, pp. 1918-29, (2008) (PubMed).

Details zu RPS6

Target: RPS6 (Ribosomal Protein S6 (RPS6))

Andere Bezeichnung: RPS6

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Molekulargewicht: 28681

NCBI Accession: NP_001001

UniProt: P62753

Pathways: Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly