RBPMS Antikörper (C-Term)

Produktnummer ABIN1881736

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RBPMS in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RBPMS Antikörper (C-Term) (ABIN1881736)

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBPMS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42810

Produktdetails anti-RBPMS Antikörper

Bindungsspezifität: AA 166-193, C-Term

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RBPMS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the C-terminal region of human RBPMS.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu RBPMS

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Andere Bezeichnung: RBPMS

Hintergrund: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.

Molekulargewicht: 21802

NCBI Accession: NP_001008710, NP_001008711, NP_001008712, NP_006858

UniProt: Q93062